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Overview Cirrhosis, the final stage of untreated chronic liver disease (see Chapter 7 ), is primarily attributable to alcohol abuse, viral hepatitis C (see Chapter 68 ), and, increasingly, nonalcoholic steatohepatitis (NASH; see Chapter 69 ) in the United States…
Abbreviations AFLD alcoholic fatty liver disease AIH autoimmune hepatitis AMA antimitochondrial antibody ANA antinuclear antibody BMI body mass index CCa cholangiocarcinoma CD68 cluster designation 68 CMV cytomegalovirus CRP C-reactive protein DILI drug-induced liver injury DM diabetes mellitus DN dysplastic nodule…

Spectrum of fatty liver disease Thomas Addison, known for his description of the eponymous disease, was the first to use the term ‘fatty liver’ in the English medical literature in 1836, most likely referring to alcohol-related liver disease (ALD). Three…