It is estimated that up to 25% of the population reports the presence of joint hypermobility, but a quarter of the population does not have an associated connective tissue disorder, nor is the increased mobility deemed a health concern; nonetheless,…
Paroxysmal disorders can be broadly classified into epileptiform and nonepileptic events. The nonepileptic episodes are often referred to by the generic term spells . They may mimic epileptic seizures but are not associated with the typical rhythmic EEG patterns characteristic…
With advancing genomic technology, disorders previously identified to be unique phenotypes are now recognized as sharing common pathways or developmental mechanisms. The clinical diagnostic paradigm is evolving to a “genomic” first approach and is less reliant on the detailed phenotype…