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Key Points Chlamydia trachomatis , the most common notifiable condition in the United States, is the most common bacterial cause of sexually transmitted disease in the United States and its prevalence is rising. The most sensitive method for detecting C.…

Key Points Human disease caused by spirochetes typically follows a clinical course that reflects three sequential phenomena: (1) early, local proliferation of the organisms at the site of introduction, (2) spirochetemia with systemic dissemination, and (3) persistence of small numbers…