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The metabolism of folate and that of cobalamin are intimately intertwined, and deficiency of either vitamin can manifest as megaloblastic anemia. The two deficiencies must be rigorously differentiated and treated specifically because their causes, mechanisms, nonhematologic expressions, courses, and prognoses…

Introduction Acute rheumatic fever (ARF) is an immune-mediated, nonsuppurative consequence of group A β-hemolytic streptococcus (GAS) infection. Although episodes of ARF can result in significant disability, the major impact of ARF at the population level is that it causes long-term,…