David Pleasure Archives - Clinical Tree

Physical Address

304 North Cardinal St.
Dorchester Center, MA 02124

Trophic Factor, Nutritional, and Hormonal Regulation of Brain Development

Introduction This chapter reviews advances in our understanding of the roles of neurotrophic proteins, retinoids, folate, lipids, and thyroid and steroid hormones in neural development. These molecules play central roles in the regulation of neuronal and glial lineages; when they…

Toxic Neuropathies

Introduction In a sense, all peripheral nervous system (PNS) disorders caused by toxic molecules are toxic neuropathies. Even normal PNS proteins can have deleterious effects if overexpressed. For example, Charcot-Marie-Tooth syndrome type 1A (hereditary motor and sensory neuropathy type 1A)…