Overview of Sellar Region Masses The overwhelming majority of sellar region masses are pituitary adenomas (85%), followed by craniopharyngioma (3%), Rathke cleft cyst (2%), meningioma (1%), and metastases (0.5%); other lesions such as hypophysitis, pituicytoma, spindle cell oncocytoma, and granular…
Normal Anatomy Dauntingly complex and characterized by extraordinary variation in regional architecture, the gross and microscopic anatomy of the human central nervous system (CNS) cannot be surveyed here in detail. Instead, a brief review of anatomic landmarks and topographic relationships…
The principal functional unit of the central nervous system (CNS) is the neuron . Neurons of different types and in different locations have distinct properties, including diverse functional roles, patterns of synaptic connections, neurotransmitters used, and metabolic requirements, which vary…
Gliomas and glioneuronal tumors constitute the largest and most heterogeneous group of primary central nervous system (CNS) tumors. Normal glia include astrocytes, oligodendrocytes, and ependyma; gliomas are analogously designated as astrocytomas, oligodendrogliomas, and ependymomas to reflect the nonneoplastic cell types…