Tag Alan David Kaye

Glucocorticoids

Uses Used to treat a wide range of illnesses including but not limited to autoimmune disorders, postop nausea and vomiting, and chronic pain Overview/Pharmacology Adrenal cortex produces and releases two different types of corticosteroids: Mineralocorticoids (maintain salt and fluid balance)…

Antipsychotics

Uses/Risk In a given year, 26.2% of Americans 18 y or older have some form of mental disorder. Schizophrenia has a community prevalence rate of 1%. Psychiatric disorders such as schizophrenia, bipolar disorder, major depression, and disorders with psychotic features…

Schizophrenia

Risk Most common psychotic disorder with a lifetime worldwide prevalence of 1% Increased risk of suicide (5–10%) Perioperative Risks Marked by deterioration of function and self-care Exacerbation of psychosis with abrupt discontinuation of medications Worry About Pt being uncooperative, combative,…

Multiple Myeloma

Risk Represents 1.6% of all new cancer cases in USA; estimated 26,850 new cases in 2015. Estimated 11,240 deaths, or 1.9% of all cancer deaths in USA in 2015. Incidence: 7.5:100,000 white males; 4.5:100,000 white females; 15.1:100,000 black males; 11.2:100,000…

Lipidemias

Risk Prevalence in USA: 13.1% in people >20 y. Prevalence highest among Hispanics. Cigarette smoking is a risk factor. Incidence highest among men ≥45 y and women ≥55 y. Htn is a risk factor. Low HDL (<40 mg/dL) is a…

Hypopituitarism

Risk Incidence: 45.5:100,000. 30% of pituitary macroadenomas (>10 mm) cause one or more hormone deficiencies. About 4.2 years after pituitary radiation therapy, some 50% of pts have hypopituitarism. Less common causes include empty sella syndrome, head trauma, infiltrative disease, and…

Hyponatremia

Risk Preop hyponatremia is a prognostic marker for increased 30-d mortality, major cardiac events, wound infection, and pneumonia. Premenopausal women, especially those undergoing procedures associated with rapid irrigant absorption, are at particularly high risk of both symptomatic hyponatremia and osmotic…