Punctate Inner Choroidopathy (PIC)


History of Present Illness

A 39-year-old woman with no significant past medical history presents to the eye clinic for the first time complaining of blurred central vision right eye (OD), with photopsias and a central blind spot (scotoma) of 1 week duration.

Exam
OD OS
Visual acuity 20/60 20/20
Intraocular pressure (IOP) 11 10
Sclera/conjunctiva Within normal limits (WNL) WNL
Cornea Clear Clear
AC No cell or flare No cell or flare
Iris WNL WNL
Lens Mild nuclear sclerosis Mild nuclear sclerosis
Vitreous cavity No cells No cells
Retina/optic nerve Normal optic nerve. Several punctate chorioretinal lesions within the arcades and paramacular ( Fig. 31.1 ) Normal optic nerve. No punctate chorioretinal lesions within the arcades

Fig. 31.1, Several punctate chorioretinal lesions within the arcades and paramacular area OD.

Questions to Ask

  • Have you had any recent infection or systemic illness?

  • Have you had an episode like this before in either eye?

  • Are you near-sighted and have you had any corrective surgery for near-sightedness?

  • Do you have metamorphopsia in your left eye (OS)?

She has no recent respiratory infection or systemic illness. She does not recall having an episode like this in either eye. She does not wear glasses because she had laser in situ keratomileusis (LASIK) surgery, but she was moderately myopic (−4.00) both eyes (OU). There is no distortion or metamorphopsia in either eye.

Assessment

  • Multifocal punctate chorioretinal lesions, OD, with presumed focal chorioretinitis OD

Differential Diagnosis

  • Punctate inner choroidopathy (PIC)

  • Multifocal choroiditis with panuveitis (MFCPU)

  • Multifocal choroiditis with subretinal fibrosis (MFC-subretinal fibrosis)

  • Multiple evanescent white dot syndrome (MEWDS)

  • Sarcoidosis

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