Penile basal cell carcinoma

Epidemiology

• Very rare, only less than 50 cases reported even when scrotal tumors are included

• Age range: 37–87 (usually above 40)

• White men mostly

• Etiology includes UV light, prior trauma, dermatitis, and prolonged irritation from truss in the etiology

• Other risk factors: Ionizing radiation, arsenic ingestion, phimosis, trauma, chronic dermatitis, immunosuppression, and inherited syndromes such as nevoid basal cell carcinoma syndrome and xeroderma pigmentosum

• No association with HPV infection