KEY FACTS Terminology Squamous cell carcinoma (SCCa) arising from mucosa overlying posterior cricoid cartilage 1 of 3 subsites of hypopharynx (HP) You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here
KEY FACTS Terminology Definition: Mucosal squamous cell carcinoma (SCCa) of pyriform sinus (PyrS) hypopharynx subsite 2/3 of all hypopharyngeal SCCa are in PyrS You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here
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KEY FACTS Terminology Hard palate squamous cell carcinoma (SCCa) Oral cavity subsite: Mucosal malignancy of roof of mouth You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here
KEY FACTS Terminology Buccal mucosa squamous cell carcinoma Oral cavity mucosal malignancy arising from inner lining of cheek and lips You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here
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KEY FACTS Terminology Squamous cell carcinoma (SCCa) arising from mucosa adjacent to teeth-bearing bone You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here
KEY FACTS Terminology Floor of mouth (FOM) squamous cell carcinoma (SCCa) Anatomic definition: FOM mucosa overlies mylohyoid and hyoglossus muscles, and body of tongue rests on it You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here
KEY FACTS Terminology Definition: Oral cavity mucosal malignancy arising from anterior 2/3 of tongue You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here
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KEY FACTS Terminology Human papillomavirus-related [HPV(+)] oropharyngeal squamous cell carcinoma (SCCa) Most often HPV type 16 You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here
KEY FACTS Terminology Definition: Squamous cell carcinoma (SCCa) arising from posterior oropharyngeal wall Soft palate is superior limit; hyoid is inferior limit You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here
KEY FACTS Terminology Palatine tonsil squamous cell carcinoma (SCCa) Most common oropharyngeal SCCa subsite You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here
KEY FACTS Terminology Base of tongue (BOT) squamous cell carcinoma (SCCa) BOT: Tonsillar tissue at posterior 1/3 of tongue You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here
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KEY FACTS Terminology Nasopharyngeal carcinoma (NPCa) Mucosal tumor most commonly found in lateral pharyngeal recess (fossa of Rosenmüller), strongly associated with EBV infection You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here
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Summary Thoughts: Squamous Cell Carcinoma Squamous cell carcinoma (SCCa) is, without question, the most common malignancy in the H&N. Recent developments in the understanding of the molecular nature and causes of SCCa now reveal it to be a heterogeneous malignancy. In most sites of the H&N, tobacco is the most common causative agent in the development of mucosal dysplasia and neoplasia. Alcohol is a synergistic cofactor,…
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KEY FACTS Terminology Abbreviation: Osteoradionecrosis (ORN) Definition: Complication of radiation therapy (XRT) with necrosis of bone and failure to heal You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here