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Nonprostatic adenocarcinoma involving the prostate


Definition

  • Metastatic adenocarcinomas to the prostate are secondary adenocarcinomas that have spread to the prostate gland via angiolymphatic invasion.

  • More commonly, adenocarcinomas from contiguous organs (e.g., bladder and colorectum) directly invade the prostate.

Clinical features

Epidemiology

  • Distant metastases to the prostate from adenocarcinomas arising in noncontiguous organs (e.g., the lung) are exceptionally rare in clinical specimens.

  • They are typically noted only with disseminated disease at autopsy (5% of cases in some series).

  • The most common adenocarcinomas that directly invade the prostate originate from the urinary bladder, colon/rectum, or urethra.

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