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Rheumatic fever. This usually occurs in early childhood, and many patients do not recall their illness.
Women, by a ratio of 2:1.
Dyspnea on exertion.
On auscultation, an opening snap and a diastolic murmur best heard at the apex.
Echocardiography: Transesophageal echocardiography is most accurate (but not always necessary).
Normal is 4–6 cm 2
Mild mitral stenosis is <2 cm 2
Severe mitral stenosis is <1 cm 2
A formula used to calculate the area of a heart valve. In simplified terms:
Mitral valve area = cardiac output (CO) ÷ √mean pressure gradient across the valve
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