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D efinition — A proliferation of specialized cuboidal cells derived from the squamocolumnar junction that gives rise to reserve cells, squamous metaplasia, and can harbor squamous intraepithelial lesions (SILs).
Most commonly occurs in young women with an uncertain relationship to hormones.
Occasionally occurs in women not receiving hormonal therapy, as well as postmenopausal women.
Likely a proliferation of multipotential squamocolumnar junction–type cells.
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