Microglandular Hyperplasia of the Cervix


D efinition A proliferation of specialized cuboidal cells derived from the squamocolumnar junction that gives rise to reserve cells, squamous metaplasia, and can harbor squamous intraepithelial lesions (SILs).

Clinical Features

Epidemiology

  • Most commonly occurs in young women with an uncertain relationship to hormones.

  • Occasionally occurs in women not receiving hormonal therapy, as well as postmenopausal women.

  • Likely a proliferation of multipotential squamocolumnar junction–type cells.

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