Mediastinal Masses


Acknowledgment

I wish to thank Dr. Frank Gencorelli for his work on this chapter in the earlier edition of this book.

Risk

  • Usually a congenital lesion, occurring at 1:5000; no gender bias

  • Benign or malignant; cysts or aneurysms that arise from the lung, pleura, or another structure of anterior mediastinum; middle mediastinum: LN enlargement and vascular masses, posterior mediastinum: neurogenic tumors and esophageal abnormalities. In children, neurogenic tumors or cysts are common.

  • Lymphoma (Hodgkin or NHL), thymoma, germ cell tumor, granuloma, bronchogenic cancer, thyroid tumors (retrosternal goiter), bronchogenic cysts, and cystic hygroma.

Perioperative Risks

  • Periop mortality is rare.

  • Sudden CV collapse from inability to ventilate or oxygenate.

  • Hypotension or tamponade.

  • Increased dyspnea (orthopnea) or cough when supine (increased risk of airway complications).

  • Syncopal symptoms or pericardial effusion (increased risk of CV complications).

  • Major airway complications in these pts are now more likely to occur in the postanesthetic care area rather than in the OR.

Worry About

  • Inability to get on cardiopulmonary bypass rapid enough to avoid permanent neurologic damage

  • Superior vena cava syndrome with airway edema and increased bleeding

  • Recurrent laryngeal nerve injury

  • Pts at risk with cough and pain, dyspnea and dysphagia, superior vena cava syndrome, tracheal deviation, Horner syndrome, cyanosis, mediastinal widening, and hoarseness

Overview

  • Severity of symptoms does not predict intraop course.

  • Airway obstruction or hemodynamic compromise has occurred with induction of GA, intubation, muscle relaxation, position change, and after extubation.

  • Pts may present with Sx that include chest pain or fullness, dyspnea, cough, sweats, superior vena cava obstruction, hoarseness, syncope, or dysphagia.

  • Pts can be asymptomatic and have a mass diagnosed on a screening chest radiograph or CT scan.

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