See also Antidysrhythmic drugs

General information

The clinical pharmacology, clinical use, efficacy, and adverse effects of lorcainide have been reviewed [ ]. The adverse effects of lorcainide may be partly caused by its active metabolite, norlorcainide, which accumulates during treatment [ ].

Organs and systems

Cardiovascular

Cardiovascular effects of lorcainide are reportedly uncommon (under 1% of cases) and have mostly been associated with intravenous administration. They include hypotension [ ] and heart block. Pre-existing sinoatrial disease and heart block are contraindications to the use of lorcainide [ ].

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