Heart Disease in Racially and Ethnically Diverse Populations


Acknowledgments

The authors thank Mercedes Carnethon, coauthor of this chapter from the previous edition of Heart Disease , for her contributions.

Additional content is available online at Elsevier eBooks for Practicing Clinicians

Epidemiology of Cardiovascular Disease in Heterogeneous Populations

Cardiovascular Disease in Racial and Ethnic Groups

According to the 2017 National Center for Health Statistics (NHIS), the burden of coronary heart diseases (CHDs) varies by racial or ethnic group. Although death rates from heart disease are declining for all race/ethnic groups, the rate of decline has been slower for race-ethnic minorities. In 2000, the age-adjusted death rate for heart disease was 326.5 per 100,000 people among non-Hispanic (NH) Blacks compared with 253.6 deaths per 100,000 among NH whites. In 2017, the age-adjusted death rate had declined to 208.0 per 100,000 people among NH Blacks compared with 168.9 deaths per 100,000 among NH whites, thus preserving the higher rate of death for Blacks observed in 2000. For Blacks and whites in the Atherosclerosis Risk In Communities (ARIC), Cardiovascular Health Study (CHS), and Reasons for Geographic And Racial Differences in Stroke (REGARDS) study, Black men were twice as likely to experience fatal CHD as white men (age-adjusted hazard ratio [HR], 2.09; 95% confidence interval [CI], 1.42 to 3.06), and Black women were more than twice as likely experience fatal CHD than white women (HR, 2.61; 95% CI, 1.57 to 4.34). These differences in fatal CHD were largely attributable to social determinants of health and cardiovascular risk factors. Disparities in stroke prevalence and incidence are even greater.

Hypertension (see also Chapter 26 )

Blacks have higher rates of hypertension than other racial or ethnic groups. Several proposed mechanisms may contribute to an increased incidence in Blacks ( Fig. 93.1 ). Figure 93.2 presents the epidemiology of hypertension awareness, treatment, and control (see Fig. 93.3A-C ) in the United States. Although rates of awareness in Blacks are higher (see Fig. 93.3A ) than in other groups, and Blacks are more likely to be on treatment (see Fig. 93.3B ) and use more medications to treat hypertension, Blacks have a lower rate of control than other racial or ethnic groups (see Fig. 93.3C ). American Indian/Alaska Natives (27.2%) also have higher rates of hypertension than Native Hawaiian or Other Pacific Islander (PI) (24.0%), Hispanic or LatinX (23.7%), white (24.8%), or Asian adults (21.9%).

FIGURE 93.1, Proposed mechanisms for the increased incidence of hypertension in Blacks.

FIGURE 93.2, Epidemiology of adults with hypertension by race/ethnicity, United States.

FIGURE 93.3, Heart failure phenotype in the Asian diaspora.

Among Hispanics/LatinXs, the hypertension prevalence varies considerably by subgroup. In the Hispanic Community Health Study/Study of LatinXs (HCHS/SOL), which measured blood pressure in 16,415 Hispanics/LatinXs (but does not include a comparison population of NHs), rates were highest among participants from Cuban, Puerto Rican, and Dominican ethnic backgrounds. Hispanics/LatinXs are less likely to be aware of their hypertension and less likely to be treated than NH whites. ,

National estimates of hypertension prevalence based on measured blood pressure in Asian Americans are lacking. Amongst the six largest Asian American populations (Asian Indian, Chinese, Filipino, Japanese, Korean, Vietnamese), Filipinos have particularly high rates of hypertension (53.2% to 59.9%), with poor awareness and control rates. Filipino patients of older age, those with comorbid medical conditions, and those who did not smoke had improved hypertension treatment, and patients with health insurance had better blood pressure control. These findings suggest that better access to health care and an approach targeted toward multiple risk factors are needed to decrease the hypertension prevalence and risk among Filipinos.

Type 2 Diabetes (see also Chapter 31 )

The overall age-standardized prevalence of diabetes in the U.S. population is 14.6%, but Hispanics/LatinXs (16.6%), Blacks (18.3%), and Asians (16.4%) have a higher prevalence than NH whites (13.3%).

The diabetes prevalence largely parallels the “epidemic” of obesity and physical inactivity, with evidence of disparities emerging even in childhood. , In the Hispanic/LatinX community, Dominicans, Puerto Ricans, and Mexicans (17% to 18%) seem to have a higher prevalence than South Americans and Cubans (10% to 13%). Emerging research comparing the relative contributions of socioeconomic, environmental, and psychosocial factors, plus ancestry, to diabetes disparities has indicated that socioeconomic factors make up the largest group of mediating factors.

Although the prevalence of diabetes generally parallels the obesity epidemic in most race/ethnic groups, this has not been the case for Asian Americans. Asian Americans have on average a lower body mass index than other racial or ethnic groups but also display evidence of insulin resistance at lower values of body mass index which may be partly explained by differences in body fat distribution (see also Chapter 30 ). , PIs, South Asians, and Filipinos have prevalence of diabetes at least twofold to threefold higher than NH whites; prevalence of diabetes is also greater in Chinese, Japanese, Korean, and Southeast Asian adults compared with whites, although the magnitude of difference is less. Filipinos and South/East Asians have higher rates of treatment than NH whites.

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