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Granulosa Cell Tumor Variants


PITFALL

D efinition — Diagnostically challenging variant patterns include those with nuclear atypia, cystic architecture, thecoma-like, luteinized, and sertoliform.

Clinical Features

Epidemiology

  • Uncommon. The granulosa cell tumor (GCT) comprises less than 2% of ovarian tumors. Over 90% will be adult type (versus juvenile GCT).

  • Perimenopausal or postmenopausal women.

  • Mean age at presentation is in the mid-50s.

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