Glomus Jugulare Tumors


Risk

  • Account for 0.6% of head and neck tumors worldwide

  • Male-to-female prevalence ratio: 1:2.5

  • Slow-growing

  • Can coexist with other paragangliomas

  • Histologically benign but can be malignant with metastases

  • Can be familial

Perioperative Risks

  • Hypothermia

  • Massive blood loss

  • Venous air embolism

  • Htn

  • Bradycardia

  • Hypotension

  • Bronchospasm

  • Tumor-parts embolization

Worry About

  • Glomus jugulare tumors can appear in multiple locations; symptoms can persist after resection of the tumor.

Overview

  • Tumors of neural crest at base of skull in jugular bulb area

  • Highly vascular

  • May extend into the posterior fossa

  • May cause hydrocephalus

  • May damage the lower cranial nerves (IX–XII)

  • May involve internal carotid artery

  • May grow into lumen of the jugular vein, as far as the RA

  • May cause Horner syndrome

  • May secrete catecholamines: 5%

  • May secrete serotonin, histamine

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