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Account for 0.6% of head and neck tumors worldwide
Male-to-female prevalence ratio: 1:2.5
Slow-growing
Can coexist with other paragangliomas
Histologically benign but can be malignant with metastases
Can be familial
Hypothermia
Massive blood loss
Venous air embolism
Htn
Bradycardia
Hypotension
Bronchospasm
Tumor-parts embolization
Glomus jugulare tumors can appear in multiple locations; symptoms can persist after resection of the tumor.
Tumors of neural crest at base of skull in jugular bulb area
Highly vascular
May extend into the posterior fossa
May cause hydrocephalus
May damage the lower cranial nerves (IX–XII)
May involve internal carotid artery
May grow into lumen of the jugular vein, as far as the RA
May cause Horner syndrome
May secrete catecholamines: 5%
May secrete serotonin, histamine
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