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Gastroparesis and Gastric Motility Disorders


Gastroparesis is defined as delayed emptying of the stomach. The most common causes of this motility disturbance of the stomach encountered in clinical practice are the association with diabetes mellitus and idiopathic forms ( Fig. 25.1 and Box 25.1 ). Gastroparesis affects persons of almost any age, with no gender predilection.

Fig. 25.1
Gastroparesis and Gastric Motility Disorders.

Box 25.1
Causes of Gastroparesis

Metabolic

  • Diabetes mellitus

  • Hypothyroidism

  • Pregnancy

  • Uremia

Associated Gastric/Esophageal Disease

  • Gastroesophageal reflux

  • Gastritis

  • Atrophic gastritis

  • Peptic ulcer disease of stomach

  • Acute gastroenteritis

Associated Diseases

  • Muscular dystrophy

  • Parkinson disease

  • Scleroderma

  • Amyloidosis

  • Chronic liver disease

  • Idiopathic pseudo-obstruction

  • Anorexia nervosa

  • Postsurgical and other trauma

  • Vagotomy

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