Erectile dysfunction is failure in the adult male to sustain an adequate erection. Erectile dysfunction leads to and can be caused by psychological problems, often with relationship breakdown. Psychological causes of impotence are common, but the most common organic disease is diabetes mellitus.

Causes

Endocrine

  • Diabetes mellitus

  • Hyperlipidaemia

  • Hypogonadism

  • Hypothyroidism

  • Cushing’s syndrome

  • Metabolic syndrome

  • Addison’s disease

Vascular

  • Diabetic vascular disease

  • Aortoiliac disease (Leriche’s syndrome)

Neurological

  • Spinal lesions

  • Neuropathies (e.g. diabetes)

  • Spina bifida

  • Pelvic surgery (damage to nervi erigentes)

Drugs

  • Antihypertensives

  • Antidepressants

  • Alcohol

  • Beta-blockers

  • Oestrogens

  • Cocaine

  • Smoking

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