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Endometrioma with Atypia

D efinition — Endometriotic epithelium with noncomplex architecture and nuclear atypia.

Clinical Features

Pathogenesis

Occurs in endometriotic cysts. Possibly a very early neoplastic change akin to other lesions associated with endometriomas, such as müllerian mucinous cystadenomas, adenofibromas, and well-differentiated endometrioid adenocarcinomas. Can be associated with mutations in ARID1A.

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