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Differentiated Vulvar Intraepithelial Neoplasia
D efinition —Vulvar intraepithelial neoplasia (VIN) that likely is secondary to a series of host gene alterations that are discrete from those involved in classic VIN.
Clinical Features
Epidemiology
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Occurs in postmenopausal women but can be seen earlier.
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Associated with less than 5% of all diagnosed cases of VIN.
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Typically associated with chronic vulvar inflammatory disease (lichen sclerosus or lichen simplex chronicus).
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