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D efinition — An expansion of the ovarian cortex and medulla by a benign proliferation of ovarian cortical stromal cells and associated luteinized cells. Cortical stromal hyperplasia (CSH) is a mild form seen at menopause; stromal hyperthecosis is a more pronounced variant associated with symptoms comparable to polycystic ovarian syndrome.
Seen in perimenopausal or postmenopausal women.
May less commonly be seen as part of the clinical spectrum of polycystic ovarian syndrome (PCOS).
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