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Clubbing is the selective bulbous enlargement of the distal segments of fingers or toes due to proliferation of connective tissues ( Fig. 10 ).
Bronchial carcinoma
Chronic suppurative lung disease
Bronchiectasis
Lung abscess
Empyema
Cystic fibrosis
Interstitial lung disease (fibrosing alveolitis, pulmonary fibrosis)
Infective endocarditis • (common in developing countries)
Congenital cyanotic heart disease
Cirrhosis
Ulcerative colitis
Crohn’s disease
Coeliac disease
Graves’ disease (hyperthyroidism)
Familial
Clubbing is said to be present when there is loss of the normal angle between the base of the nail and the nailfold. In the presence of clubbing, when the fingernails from each hand are placed together, the gap is lost, and this is known as Schamroth’s sign. Other features are increased curvature of the nailbed (in all directions), sponginess or fluctuation and expansion of the end of the digit to resemble a drumstick.
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