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Cervical Conization (Cold Knife)
Description
Cervical conization is a diagnostic or therapeutic procedure that removes a cone-shaped specimen from the uterine cervix. Cold knife cone biopsy used to be the preferred treatment for removing abnormal cells, but now most cone biopsies are performed using the wire loop and electrosurgical energy (loop electrosurgical excision procedure [LEEP]/large loop excision of the transformation zone [LLETZ] cone). Cold knife cone biopsy is generally used for special situations such as when the size or shape of the specimen must be customized to a greater degree than allowed by loop procedures.
Indications
Histologically verified advanced epithelial atypia (for diagnosis or therapy) or inability to adequately evaluate the cervix through colposcopy.
Contraindications
Coagulopathy, advanced pregnancy, known or suspected allergy to the agents used.
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