Category Pediatrics

Rheumatology

Clinical issues 1 What is an antinuclear antibody (ANA)? ANA is made up of circulating γ-globulins directed against several known and unknown nuclear proteins. Unfortunately, the classic immunofluorescence technique is being replaced by a still nonvalidated enzyme-linked immunosorbent assay (ELISA)…

Pulmonology

Acknowledgment The editor gratefully acknowledges contributions by Drs. Robert W. Wilmott, Bradley A. Becker, Ellen R. Kaplan, Carlos R. Perez, William D. Hardie, Barbara A. Chini, and Cori L. Daines that were retained from previous editions of Pediatric Secrets .…