Autopsy Authorization The laws pertaining to authorization for autopsy vary among the states. Local jurisdictions may establish policies or procedures for compliance, and it behooves the practicing pathologist to know the relevant statutes in his or her region. In the…
The quotation above (Latin for “the dead teach the living”) historically has been cited either literally, as justification for examination of cadavers to learn anatomy and investigate pathology, or figuratively, to indicate learning from the work of past scholars. This…
Introduction See Chapter 28 under Medullary Thyroid Carcinoma for additional discussion. Multiple endocrine neoplastic (MEN) syndromes represent primarily autosomal dominant inherited disorders characterized by hyperplastic or neoplastic proliferations of more than one endocrine gland and include: MEN type 1 MEN…
Considerations Optimal management of primary hyperparathyroidism is achieved by selective removal of parathyroid glands guided by the histologic findings in each gland. Surgical management of a patient with primary hyperparathyroidism is to remove one or more enlarged parathyroid glands. Pathologists…
Classification of Neoplasms of the Parathyroid Glands ( Box 33-1 ) Box 33-1 Neoplasms of the Parathyroid Glands Parathyroid adenoma Parathyroid carcinoma Secondary neoplasms Parathyroid Adenoma ( Figs. 33-1 through 33-22 , Table 33-1 ) Definition: Benign neoplasm of the…
Classification of Non-Neoplastic Lesions of the Parathyroid Glands (Box 32-1) Box 32-1 Non-Neoplastic Lesions of the Parathyroid Glands Parathyroid hyperplasia – Primary chief cell hyperplasia – Water-clear cell hyperplasia Parathyroiditis Parathyroid cyst Primary Chief Cell Hyperplasia ( Figs. 32-1 through…
Hyperparathyroidism Definition: Hyperparathyroidism is the state of elevated serum parathyroid hormone (PTH) as a result of excessive secretion (overproduction). Hyperparathyroidism is the most common pathologic condition affecting the parathyroid glands. Causes of hyperparathyroidism due to parathyroid-related disorders are listed in…
Embryology Parathyroid glands are of endodermal origin and originate as symmetric, nodular epithelial proliferations on the dorsal aspects of the third and fourth pharyngeal pouches around the fifth week of gestation. Superior gland develops from the fourth pharyngeal pouch, which…
Post Fine Needle Aspiration Biopsy (FNAB)-Related Morphologic Changes ( Figs. 29-1 through 29-11 ) FNAB has tremendous utility as first interventional diagnostic procedure relative to a patient with a thyroid mass. Diagnostic sensitivity and specificity of FNAB of a thyroid…
Classification of Neoplasms of The Thyroid Gland See Box 28-1 . Box 28-1 Classification of Thyroid Gland Neoplasms Follicular Epithelial Origin Benign Follicular adenoma and variants Malignant Follicular carcinoma and variants Papillary carcinoma and variants Poorly differentiated carcinoma Undifferentiated (anaplastic)…