Introduction Vulvodynia is defined as a chronic discomfort or pain, consisting of burning, stinging, irritation, and rawness on the vulva. It was once believed to be a rare condition, but is now known to affect millions of women. It can…
Introduction Diagnostic dermatopathology of the vulva is a field that may be practiced on a multitude of levels. Patients may be seen by gynecologists, family practitioners, internists, or dermatologists. The biopsy may be read by a dermatopathologist, gynecologic pathologist, or…
Overview of Reproductive Tract Development The female genital tract is formed by a complex series of events beginning in the fourth week of development. This process involves the formation of the gonads following germ cell migration from the yolk sac…
Benign tumors Superficial Angiomyxoma Definition An uncommon distinct type of myxoma characterized by the presence of thin-walled blood vessels This is likely to represent the same entity as cutaneous myxoma, including the lesions seen in Carney complex Clinical features Epidemiology…
Reactive lesions Traumatic Neuroma Definition A reactive/reparative process characterized by proliferation of axons, Schwann cells, and perineurial fibroblasts in a disorganized pattern in the background of collagenous stroma (scar) at the proximal end of an injured/severed peripheral, cranial, or autonomic…
Benign tumors and reactive proliferations Osteoma Cutis Definition Osteoma cutis represents a reactive, metaplastic, lamellar bone formation in the dermis and/or subcutis Primary and secondary forms of osteoma cutis can be separated on the basis of the absence or presence…
Benign tumors including reactive vascular proliferations and ectasias Intravascular Papillary Endothelial Hyperplasia (Masson tumor) Definition A nonneoplastic, reactive, endothelial proliferation representing an organizing thrombus, characterized by formation of arborizing and interconnecting intravascular papillary cores lined by endothelial cells Clinical features…
Benign tumors Rhabdomyomatous Mesenchymal Hamartoma Definition A rare dermal or subcutaneous benign lesion composed of disordered mature elements, including skeletal muscle, adipose tissue, nerve bundles, blood vessels, adnexal tissue, and collagen Initially reported as striated muscle hamartoma Additional terms used…
Benign tumors Glomus Tumor Definition A benign tumor composed of modified smooth muscle cells (e.g., glomus cells) Subclassified into three groups based on the proportions of glomus cells, blood vessels, and (perivascular) smooth muscle cells into: Classical or solid glomus…
Benign tumors and hamartomas Smooth Muscle Hamartoma Definition A hamartomatous lesion composed of a dermal proliferation of mature smooth muscle cells growing in haphazardly arranged bundles Clinical features Epidemiology Slight male predominance Prevalence of 1 in about 2700 live births…