See also Anticholinergic drugs and Ipratropium bromide General information Oxitropium is an anticholinergic drug used in the treatment of asthma [ ]. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership…
See also Antiepileptic drugs and Carbamazepine General information Oxcarbazepine is the 10-keto analogue of carbamazepine and a prodrug for monohydroxycarbazepine, to which it is rapidly reduced. Its efficacy and tolerability profiles are similar to those of carbamazepine, from which oxcarbazepine…
General information When first marketed, the oxazolidinones represented the first truly new class of antibacterial agents to reach the marketplace in several decades [ ]. They have a unique mechanism of action, involving inhibition of the first step in protein…
See also Benzodiazepines General information Oxazepam, which is a metabolite of temazepam and desmethyldiazepam, is itself used as a benzodiazepine for the management of insomnia. It is slowly absorbed, has a relatively short half-life (5–15 hours), and is metabolized primarily…
See also Antihistamines General information Oxatomide is a second-generation antihistamine [ ]. Organs and systems You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in…
General information In controlled studies, oxaprozin caused adverse effects in 23–58% of patients [ ]. It was considered better than aspirin and similar to other NSAIDs in long-term studies [ ]. However, treatment had to be interrupted owing to adverse…
General information Oxamniquine, in doses of 15 mg/kg or in a single oral dose of up to 15 mg/kg bd for 2 days, depending on the sensitivity of Schistosoma mansoni in the area concerned, is effective with minimal toxicity. It…
See also : Non-steroidal anti-inflammatory drugs (NSAIDs) General information The adverse reactions pattern of oxametacin is similar to that of indometacin. In one study, 17% of 771 patients taking oxametacin had adverse effects, which led to withdrawal of treatment in…
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See also Factor Xa inhibitors, direct General information Otamixaban is direct factor Xa inhibitor [ , ]. Its pharmacokinetics have been studied in healthy men over a wide range of intravenous doses, with durations of administration varying between 1-minute infusions…