Advantages of zebrafish models for cancer research Zebrafish is a preeminently suitable model organism for cancer research and has been shown to complement murine model systems to assay tumor cell malignancy, progression, and drug screening after xenotransplantation [ ]. A…
Introduction In human disease, bone metastasis is a slow process often developing years after the initial tumor is diagnosed and treated. Bone metastases are commonly only detected when patients present with late-stage symptomatic disease, at a point when extensive bone…
Acknowledgments We thank Ms Séverine (Université de Nantes, FR) for providing the micro-CT images and M Jérome Amiaud and Ms Céline Charrier (Université de Nantes, FR) for the histological preparation. You’re Reading a Preview Become a Clinical Tree membership for…
Acknowledgments The authors are indebted to Prof. E Hauben for involvement in the previous version of this book chapter. Primary bone tumors are rare and as such they form a difficult category of tumors for appropriate recognition and classification both…
Research highlights Paleopathology produces a body of evidence that illustrates the history of oncological diseases in a diachronic perspective. Cancer geographic and temporal ubiquity is not an exclusive phenomenon of the recent times. Malignant neoplasms, expressed by bone metastatic disease…