Key points Atopic dermatitis is one of the most common inflammatory diseases of the skin, with both genetic and environmental etiologies. The prevalence of atopic dermatitis is increasing globally due to changes in climate, microbes, urbanization, among other factors. Atopic…
Key points Atopy of the skin is manifested as atopic dermatitis (atopic eczema). Histologically, the atopy of the skin is characterized by epidermal and dermal infiltration predominantly by lymphocytic cells as well as eosinophils and mast cells. In some patients,…
Key points Although the original term atopy provides a general framework of understanding about allergic clinical conditions, this big umbrella now includes a group of patients who have heterogeneous clinical and laboratory-defined characteristics. Similarly, atopic dermatitis , the skin atopy,…
Key points From the historic perspective, atopic dermatitis has gone through several evolutionary periods of understanding and development. From ancient times to the 18th century, medical communities started to recognize a type of itchy skin disease. Although the term eczema…
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