Key Points Incidence It was estimated that in 2018 there would be 91,270 new cases of melanoma diagnosed and 9320 deaths in the United States. Biological Characteristics Sun exposure is clearly associated with the development of cutaneous melanoma. Inherited mutations…
Key Points Incidence Cutaneous basal cell carcinomas (BCCs) and squamous cell carcinomas (SCCs) are the most frequent cancers worldwide. Caucasian populations residing in locations with high level exposure to ultraviolet (UV) radiation, such as Australia and New Zealand and the…
Assessment and treatment of regional lymph nodes in the neck are of utmost importance in the treatment of patients with head and neck squamous cell carcinoma (HNSCC). The philosophy of treatment of the neck has evolved over the past several…
Key Points Incidence Carcinoma of an unknown primary tumor (CUP) in the head and neck describes a patient with cervical node metastases without a physically or radiologically identifiable primary tumor site. Approximately 3% of patients with head and neck squamous…
Key Points Incidence Thyroid cancer incidence in the United States increased on average 3.6% per year during 1974 to 2013 (from 4.56 per 100,000 person-years in 1974 to 1977 to 14.42 per 100,000 person-years in 2010 to 2013) mainly owing…
Key Points Incidence The overall incidence of salivary gland malignancies in the general population is about 0.9 to 4.0 new cases per 100,000 population per year. Biologic Characteristics Prognostic factors relate to histology, grade, primary tumor size and extent, lymph…
Key Points Incidence and Epidemiology Sinonasal cancers comprise less than 1% of all malignant neoplasms and the American Cancer Society estimates 2000 Americans develop cancers of the nasal cavity and paranasal sinuses annually. Men are 50% more likely to be…
Key Points Incidence Laryngeal and hypopharyngeal cancers account for about one-third of all head and neck neoplasms, affecting approximately 13,000 Americans per year. Biological Characteristics Prognosis for all tumors is primarily dependent on extent of disease, although it is also…
Key Points Incidence In the United States, nasopharyngeal carcinoma is uncommon, occurring at a rate of less than one case per 100,000 people. In contrast, in southern China and Hong Kong, the incidence is 25 to 50 per 100,000 people…
Key Points Incidence The estimated annual incidence of oropharyngeal cancer in the United States is more than 10,000 patients. The incidence of oropharyngeal cancer has gradually increased over the past several decades, particularly in younger patients. Biologic Characteristics Squamous cell…