Definition The variant of prostatic adenocarcinoma with cancer glands having a scant volume of cytoplasm, which can be mistaken for atrophy or postatrophic hyperplasia. Clinical features Epidemiology Two percent incidence in needle core cases, 16% incidence in radical prostatectomy specimens…
Definition Acinar adenocarcinoma of the prostate gland is the second most frequently diagnosed form of cancer in the United States. The National Cancer Institute estimates that almost 249,000 new cases will develop in 2021. Clinical features Epidemiology Prostate cancer is…
Definition The vast majority of cases represent the spread of prostatic adenocarcinoma into benign prostatic ducts or acini but can rarely be a precursor lesion associated with an aggressive behavior. Clinical features You’re Reading a Preview Become a Clinical Tree…
Definition Proliferation of secretory epithelial cells displaying significant architectural and cytologic atypia within the pre-existing acini and ducts Categorized into low-grade prostatic intraepithelial neoplasia (LGPIN) and high-grade (HGPIN) types Clinical features You’re Reading a Preview Become a Clinical Tree membership…
Definition Area of ischemic stromal and glandular tissue damage typically associated with BPH Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in…
Definition Benign, small acinar proliferation of the prostatic glands that occurs exclusively in the verumontanum and adjacent prostatic urethra. A potential mimic of prostate adenocarcinoma. Clinical features Epidemiology Older patients (age 47–87) Incidental finding in 14% of radical prostatectomy specimens…
Definition Neuroendocrine cells of the prostate are intraepithelial regulatory cells that regulate both growth and differentiation, as well as the exocrine secretory activity of the prostate (part of the amine precursor uptake and decarboxylation [APUD] system of endocrine-paracrine cells). These…
Definition Replacement of the normal secretory epithelium of the prostatic ducts and acini with goblet cells. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log…
Definition Replacement of the normal cuboidal/columnar secretory epithelium of the prostatic ducts and acini with benign squamous epithelium. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a…
Definition Replacement of the benign cuboidal to columnar secretory epithelium of the prostatic acini and distal ducts with benign urothelium. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you…