Uropathology

Urothelial carcinoma with squamous differentiation

Definition Urothelial carcinoma shows focal or extensive areas of keratin production or intercellular bridge formation. Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member.…

Urothelial carcinoma with inverted growth pattern

Definition Noninvasive low- or high-grade urothelial carcinoma showing an inverted–endophytic pattern of growth; may have a coexisting exophytic papillary component Clinical features Epidemiology Relatively uncommon You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited…

Invasive urothelial carcinoma

Definition Carcinoma derived from the urothelial lining of the urinary tract that invades into the underlying tissues Clinical features Epidemiology Urothelial carcinoma occurs most often in the urinary bladder with lower incidence in the kidneys, ureters, and urethra. Urothelial carcinoma…

High-grade papillary urothelial carcinoma

Definition Papillary urothelial neoplasm shows significant architectural and cytologic atypia that are apparent at low magnification Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a…

Low-grade papillary urothelial carcinoma

Definition Papillary neoplasm lined by urothelium with easily recognizable variation in cytologic features and characterized by an overall orderly appearance of the urothelium lining papillary fronds Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access…

Papillary urothelial neoplasm of low malignant potential

Definition Papillary urothelial tumor with abnormally thick urothelium, but lacking cytologic atypia Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here

Inverted papilloma

Definition Benign urothelial neoplasm with a predominant endophytic pattern of growth Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here

Urothelial papilloma

Definition Benign exophytic urothelial neoplasm characterized by simple, usually nonbranching papillary fronds lined by normal-appearing urothelium Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a…

Urothelial carcinoma in situ

Definition Flat urothelial lesion of the surface urothelium that is composed of cytologically malignant high-grade cells. Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a…

Urothelial dysplasia

Definition Presence of distinct cytological and architectural atypia in flat urothelium falling short of the diagnosis of urothelial carcinoma in situ (CIS) Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles…