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Vascular complications continue to be a major source of morbidity and mortality after orthotopic liver transplantation (OLT). Arterial complications of OLT threaten outcomes for patients and allografts. Hepatic arterial thrombosis (HAT) interrupts the allograft's blood supply and produces early graft…
Complications involving the biliary tract after orthotopic liver transplantation (OLT) have been a common problem since the beginning. Because of the limited number of donation after brain death (DBD) donors, alternative techniques and approaches such as living donor liver transplantation…
Graft failure is a serious life-threatening condition for transplant recipients, and when left untreated, it results inevitably in death of the recipient. It is important to differentiate between acute and chronic graft failure. Although acute graft failure occurs early in…
Orthotopic liver transplantation (OLT) is a well-established definitive treatment for patients with chronic advanced cirrhosis or acute fulminant hepatic failure and a viable therapeutic option for those with primary resectable hepatic malignancies with or without cirrhosis. Over the past decade…
Late adolescence and young adulthood have long been seen as a time of increased risk in life across all populations and generations. Indeed, the overall mortality rate of young adults between 18 and 24 years of age is more than…
Liver transplantation (LT) is the standard of care for children with end-stage liver disease (ESLD), acute liver failure, select patients with primary liver tumors, and certain inborn errors of metabolism. Patient survival after LT has improved significantly with advances in…
As discussed in Chapter 69 , there are various potential severe surgical and medical complications that may occur immediately after liver transplantation. Once a patient has been transferred out of the intensive care unit, the focus shifts more to rehabilitation,…
The transition from the operating room after liver transplantation to the pediatric intensive care unit (ICU) and the subsequent 48 hours are a critical time for success of the procedure. During this time there is great potential for life-threatening problems…
Nowhere else in the realm of liver transplantation have both the advances made in the field and the realities of the surgery been more evident than in the intensive care unit (ICU). The impact of the Model for End-Stage Liver…
The first reported performance of auxiliary liver transplantation (ALT) was in a dog by Welch in 1955. The auxiliary liver was placed in a heterotopic position in the right paravertebral gutter, with portal venous inflow directed from the iliac vein.…