Total Burn Care

The Pathophysiology of Inhalation Injury

Introduction and Epidemiology It has been more than three decades since Herndon and colleagues' first manuscript on inhalation injury was published. It was initially reported in 1985 that inhalation injury was a major determinant of mortality in severely burned patients.…

Skin Substitutes and ‘the next level’

Introduction Structure and Function of the Skin Skin, the body's largest organ, is incredibly complex. Functionally, there are two layers with a highly specialized and effective bonding mechanism. Numerous appendages traverse the skin, and a rich and reactive capillary network…

The Skin Bank

History The first skin autograft was described by Reverdin in 1871, and the use of allograft skin as a clinical method for wound coverage soon followed. In 1874, Thiersch published a report about a small series of patients on whom…

Anesthesia for Burned Patients

Introduction Continuous improvement in burn care since World War II has resulted in a steady increase in the rate of survival after large burn injury. These improvements have been attributed to aggressive fluid resuscitation, early excision and grafting of burn…

Operative Wound Management

Introduction Surgery for burn injury is a key component to the multidisciplinary care of the burn patient. It usually involves early procedures such as escharotomy and fasciotomy when indicated, followed by burn excision. Early intervention in the form of early…

Treatment of Infection in Burn Patients

Introduction Skin is the first immune defense mechanism and functions as a barrier against microorganisms. Infections are a significant problem once open wounds compromise this barrier. According to the U.S. National Burn Repository, the four leading causes of burn morbidity…

Evaluation of the Burn Wound: Management Decisions

Introduction Advances in the resuscitation of burn patients have greatly improved survival so that death from burn shock has become uncommon. In the 21st century, prompt functional recovery for the burn patient hinges on proper early management of the burn…

Burn Resuscitation

Note: The opinions or assertions contained herein are the private views of the authors, and are not to be construed as official or as reflecting the views of the Department of the Army or the Department of Defense. Introduction Burns…

Pathophysiology of Burn Shock and Burn Edema

Note: The opinions or assertions contained herein are the private views of the authors, and are not to be construed as official or as reflecting the views of the Department of the Army or the Department of Defense. Introduction and…