Onco-Nephrology

Kidney disease in lymphoma

Introduction Lymphoma is a hematologic malignancy caused by the abnormal proliferation of lymphoid cells. An estimated 80,000 people will be diagnosed with lymphoma in the United States in 2018. Because of more targeted therapies, patients with lymphoma are living longer.…

Kidney disease in leukemia

Introduction Leukemia is a group of hematologic malignancies derived from bone marrow cells, respectively. Although not as common as solid organ malignancies, the prevalence is estimated to be greater than 350,000 people with or in remission from leukemia in the…

Renal infections in cancer patients

Introduction Epidemiology Cancer patients are at a higher risk of infections with a mean annual incidence rate of 1465 cases per 100,000 cancer patients and a relative risk [RR] of 9.77 compared with noncancer patients (95% confidence interval [CI], 9.67–9.88).…

Cancer in renal transplant patients

Introduction Renal transplantation remains the treatment of choice for eligible candidates with end-stage renal disease (ESRD), because it offers improved quality and increased quantity of life to these patients. In the early days of renal transplantation, the lack of potent…

Incidence of cancer and screening recommendations

Introduction The purpose of cancer screening is to identify treatable cancers early to improve survival. Effective cancer screening therefore depends on cancer occurrence and risk, the availability and effectiveness of cancer screening tools, and expected survival in a given population.…

Renal replacement therapies

Introduction Acute kidney injury (AKI) occurs commonly in cancer patients and independently increases morbidity and mortality. , Despite impressive gains in the understanding of the basic pathophysiologic principles underlying kidney injury, there are no therapeutic options to prevent or ameliorate…

Obstructive nephropathy in cancer

Introduction Acute and chronic renal impairment resulting from urinary tract obstruction is common among patients with cancer and not solely limited to patients with pelvic tumors. Unlike benign causes of urinary tract obstruction, urinary obstruction resulting from malignancies poses several…

Tumor lysis syndrome

Introduction Tumor lysis syndrome (TLS) describes the series of metabolic events that result from the death of rapidly dividing cancer cells. When cancer cells die, either spontaneously or in response to chemotherapy, they lyse and release intracellular contents of electrolytes,…

Acute kidney injury incidence, pathogenesis, and outcomes

Introduction Advances in therapy, risk stratification, and supportive care have improved survival of patients with cancer over the past 2 decades. Acute kidney injury (AKI) remains a common complication of cancer treatment and entails increased length of stay, cost, and…