Introduction In the 1960s and early 1970s, histochemical stains were for the pathological examination of the routine muscle biopsy to define myofiber types and certain metabolic disturbances, and they continue to be the standard of diagnostic examination of the muscle…
Introduction This chapter discusses the use and techniques of pediatric electromyography (EMG). In a comprehensive text on neuromuscular disease such as this, targeted towards clinicians in neuromuscular medicine, the intention of this chapter is not to make readers experts in…
Introduction Many neuromuscular disorders in children are single gene disorders, and therefore genetics plays a primary role in the diagnosis of many neuromuscular conditions. Establishing a definitive molecular genetic diagnosis provides clarity about prognosis; suggests possible therapeutic strategies; allows patients,…
The field of pediatric neuromuscular disorders has continued to expand scientifically since the era of molecular neurogenetics began in the mid-1980s. The rapid changes in the field may be overwhelming to busy, practicing clinicians on a day-to-da… Introduction The role…