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General information Bucillamine (mercaptomethylpropanoylcysteine) is chemically related to penicillamine and is also used in rheumatoid arthritis. Most of the information on bucillamine comes from Japan, its country of origin [ ]. The patterns of adverse reactions to sulfhydryl compounds that…
General information Bryostatins are naturally occurring antineoplastic macrocyclic lactones derived from the marine invertebrate Bugula neritina , different varieties being isolated from different populations of the same species. More than 13 structurally related compounds have been isolated [ , ],…
See also Benzodiazepines General information Brotizolam is a triazolothienodiazepine used in the treatment of insomnia and also has anticonvulsant, antianxiety and muscle relaxant properties. It reduces latency to sleep, reduces the number of awakenings and waking time during sleep, and…
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See also Antihistamines General information Brompheniramine is a first-generation antihistamine, an alkylamine derivative, with antimuscarinic and moderate sedative actions. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are…
General information Bromocriptine is an ergot derivative. High doses (for example 30–75 mg/day orally) are used in Parkinson’s disease; low doses (2.5–5.0 mg/day) are used for prostatic tumors and to suppress lactation. The adverse reactions are dose-dependent and, so far…
General information Bromhexine is taken orally or by aerosol and reduces sputum viscosity as measured ex vivo. Although it is still used empirically by some physicians, there have been no controlled studies showing a significant improvement in clinical status or…
See also Non-steroidal anti-inflammatory drugs (NSAIDs) General information Bromfenac sodium (2-amino-3-(4-bromo-benzoyl)-benzeneacetic acid sodium salt sesquihydrate) has a safety profile apparently similar to that of other NSAIDs [ ]. It was approved by the FDA in 1997 for short-term management of…
See also Benzodiazepines General information Bromazepam, a moderately short-acting benzodiazepine (half-life about 12 hours), has been used in the treatment of anxiety states and has the usual effects of benzodiazepines, for example amnesia and depressed psychomotor performance, although it causes…