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Carnidazole
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Carisoprodol
General information Carisoprodol is a precursor of meprobamate, an oral anxiolytic with similarities to benzodiazepines. The spasmolytic effect of carisoprodol is thought to be due to interruption of neuronal communication within the reticular formation and spinal cord. Major adverse effects…
Cardiac glycosides
General information Many aspects of the pharmacology, clinical pharmacology, and adverse effects, adverse reactions, and interactions of cardiac glycosides have been reviewed [ ]. Note on nomenclature The most commonly used cardiac glycosides, digoxin and digitoxin, are derived from foxgloves,…
Carboxypeptidase G2
General information Carboxypeptidases are regulatory peptide-processing enzymes that are secreted by human cells [ ]. Carboxypeptidase G2, which is produced by Pseudomonas strain RS-16, hydrolyses the glutamate residue from methotrexate and other folate analogues [ ] and rapidly hydrolyses methotrexate…
Carboprost
See also Prostaglandins General information Carboprost is a 15-methylated analogue of PGF 2α . It is used in termination of pregnancy, in the management of labor, and to treat postpartum hemorrhage and uterine atony. Organs and systems You’re Reading a…
Carbonic anhydrase inhibitors
General information The carbonic anhydrase inhibitors, of which acetazolamide, a non-competitive inhibitor, is the prototype, are not suitable for normal diuretic use, because tolerance soon develops. However, they are well suited to brief intermittent use, particularly in the relief of…
Carbon dioxide
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Carbocisteine
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Carbenoxolone
General information Liquorice owes its ulcer-healing properties to glycyrrhizin and glycyrrhizic acid; carbenoxolone is related to the latter. All these substances have unwanted mineralocorticoid-like effects. Deglycyrrhizinated liquorice and lauryl glycyrrhetinic acid, which are also used in some countries for their…
Carbapenems
See also Beta-lactam antibiotics General information Carbapenems differ from penicillins and cephalosporins by a methylene substitution for sulfur in the five-membered beta-ring structure. Imipenem and meropenem belong to this class of compounds. Although there are various natural carbapenems [ ],…