General information Clarithromycin is a commonly used macrolide antibiotic and is a regular part of regimens for the eradication of Helicobacter pylori , often in combination with a nitroimidazole antibiotic as well, in addition to a proton pump inhibitor. Variable…
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General information Citric acid is used in effervescing mixtures and granules. Formulations that contain citric acid are used in the management of dry mouth and to dissolve renal calculi, alkalinize the urine, and prevent encrustation of urinary catheters. Citric acid…
See also Selective serotonin re-uptake inhibitors (SSRIs) General information Citalopram Citalopram is a racemic bicyclic phthalane derivative and is a highly selective serotonin re-uptake inhibitor with minimal effects on noradrenaline and dopamine neuronal reuptake. Inhibition of 5-HT re-uptake by citalopram…
General information Cisatracurium is one of the ten isomers of atracurium. With an ED 95 of 0.05 mg/kg it is about three times more potent than atracurium [ ]. The duration of action of cisatracurium tends to be slightly longer…
General information Cisapride is structurally similar to metoclopramide, but has no dopamine receptor antagonist activity and hence no central antiemetic effect. However, because it stimulates the release of acetylcholine in the gastrointestinal tract it is effective in conditions such as…
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See also Fluoroquinolones General information Ciprofloxacin is a fluoroquinolone antibacterial drug with a wider spectrum of activity than nalidixic acid. Drug studies Observational studies Antimicrobial prophylaxis to prevent inhalational anthrax has been recommended for people potentially exposed to Bacillus anthracis…
See also Antihistamines . General information Cinnarizine and flunarizine are piperazine derivatives with antihistaminic properties and calcium channel blocking activity [ ]. Flunarizine is the difluoro derivative of cinnarizine. Cinnarizine is used to treat motion sickness. A few controlled clinical…
See also Non-steroidal anti-inflammatory drugs (NSAIDs) . General information The NSAID cinmetacin is an indometacin derivative [ , ], of which there is little experience. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited…