General information Dextrans are mixtures of polymerized glucose molecules, mostly alpha-1,6-glucans, of variable molecular weight from 1 to 110 kDa. Infused dextran is mainly eliminated unmodified by the kidney at a rate of 50% in the first 24 hours and…
General information The α 2 -adrenoceptor agonist dexmedetomidine has potent sedative and analgesic-sparing properties. In therapeutic doses it does not cause respiratory depression, making it attractive for infusion sedation. However, it causes reduced sympathetic outflow, which might cause untoward hemodynamic…
General information Dexloxiglumide is a cholecystokinin CCK 1 receptor antagonist [ ]. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here
General information See also Non-steroidal anti-inflammatory drugs (NSAIDs) Dexketoprofen is the dextrorotatory stereoisomer of ketoprofen. The analgesic effect of ketoprofen is due to the S(+)-enantiomer (dexketoprofen), while the R(−)-enantiomer has no analgesic activity [ ] but may be ulcerogenic […
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General information Dexibuprofen is the dextrorotatory isomer of ibuprofen. Clinical experience is still inadequate to judge its safety profile, although there are claims that it is of comparable safety to celecoxib [ ]. Pharmacokinetics The pharmacokinetics of dexibuprofen 400 mg…
See also Antihistamines General information Dexchlorpheniramine maleate [ ] is the dextrorotatory isomer of chlorphenamine. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in…
See also Antihistamines General information Dexbrompheniramine is the dextrorotatory isomer of the first-generation H 1 antihistamine brompheniramine. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member.…
See also Amphetamines General information Dexamfetamine or (+)-amfetamine is significantly more potent than (−)-amfetamine. The use of dexamfetamine as an appetite suppressant has rapidly declined, because of appreciation of its potential for abuse and addiction. These arise mainly from euphoria,…
See also Vasopressin and analogues General information Desmopressin ( N -deamino-8- d -arginine vasopressin, dDAVP) is a longer acting analogue of vasopressin. It has very little vasoactive effect but is antidiuretic by an action on vasopressin V 2 receptors in…