See also Angiotensin-converting enzyme inhibitors General information Fosinopril is a phosphorus-containing ester prodrug of the ACE inhibitor fosinoprilat. Its clinical pharmacology, clinical use, and safety profile have been reviewed [ ]. Organs and systems You’re Reading a Preview Become a…
General information Fosfomycin is a broad-spectrum antibiotic used to treat uncomplicated lower urinary tract infections. It penetrates interstitial space fluids of soft tissues well and reaches concentrations sufficient to substantially inhibit the growth of relevant bacteria at the target site…
General information Foscarnet (trisodium phosphonoformate hexahydrate) is a pyrophosphate analogue that interacts with the enzymatic action of polymerases and inhibits the cleavage of pyrophosphate from the nucleoside triphosphate. Because of this mechanism, the antiviral activity of the drug is broad.…
See also Beta 2 -adrenoceptor agonists General information Formoterol is a long-acting selective β 2 -adrenoceptor agonist that is more potent than salmeterol [ ] and has a similar duration of action (12 hours) but a rapid onset of effect…
General information Aldehydes such as formaldehyde, glyoxal, and glutaral (glutaraldehyde) are used as solutions and vapors for disinfection and sterilization. They are irritating and sensitizing and cause contact dermatitis in health-care workers [ ]. Exposure to formaldehyde occurs in certain…
See also Hair dyes , Ocular dyes General information The US Federal Food, Drug and Cosmetic Act (1938) [ ] defined three classes of certifiable colors: 1. FD&C colors: for use in coloring food, drugs, and cosmetics. 2. D&C colors:…
See also Factor Xa inhibitors, direct General information Fondaparinux and idraparinux are indirect factor Xa inhibitors. Fondaparinux is a synthetic pentasaccharide that mimics the site of heparin that binds to antithrombin III and inhibits factor Xa activity, which in turn…
General information Fomivirsen (ISIS 2922) is an antisense oligonucleotide that specifically inhibits replication of human cytomegalovirus. It has been developed for intravitreal administration to treat cytomegalovirus retinitis in patients with AIDS. You’re Reading a Preview Become a Clinical Tree membership…
General information The first gonadotropins available for clinical use were extracted from the urine of postmenopausal women. Human menopausal gonadotropin (hMG) is in limited supply and contains other proteins, which may be allergenic, as well as luteinizing hormone. Purified preparations…
See also Vitamins General information Folic acid (pteroylglutamic acid) is a vitamin of the B group, whose Average Dietary Requirement in adults has been set at 140 micrograms/day, with a Population Reference Intake of 200 micrograms Red cell folate concentrations…