General information For a complete account of adverse reactions to estrogens, readers should consult the following monographs as well as this one: Diethylstilbestrol Estrogens Hormonal contraceptives—oral Hormone replacement therapy—estrogens Hormone replacement therapy—estrogens + androgens Hormone replacement therapy—estrogens + progestogens In…
General information For a complete account of adverse reactions to estrogens, readers should consult the following monographs as well as this one: Diethylstilbestrol; Estrogens; Hormonal contraceptives—emergency contraception; Hormone replacement therapy—estrogens; Hormone replacement therapy—estrogens + androgens; Hormone replacement therapy—estrogens + progestogens.…
See also Antihistamines General information Homochlorcyclizine is a first-generation antihistamine [ ] with high affinity for muscarinic receptors [ ] and an inhibitory effect on the release of arachidonic acid from neutrophil leukocytes [ ]. It may also be an…
General information Statins inhibit HMG-CoA reductase and reduce cellular cholesterol synthesis [ ]. Lower intracellular cholesterol concentrations cause over-expression of the LDL receptor in the plasma membrane of hepatocytes. This overexpression increases the clearance of circulating LDL, reducing plasma concentrations…
General information All the HIV protease inhibitors have in common a specific effect against the aspartic HIV protease that cleaves viral proteins to yield structural proteins. Competitive inhibition of this process by the protease inhibitors results in the production of…
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General information The family of Hippocastanaceae contains the single genus Aesculus (buckeye, horse chestnut). Aescin is the major active principle from the horse chestnut tree ( Aesculus hippocastanum ) and is claimed to have clinical activity in venous insufficiency. Investigations…
General information Hexetidine has been used as an oral cavity antiseptic and in preventing plaque and gingival inflammation [ ]. At the concentration normally used (1 mg/ml), it is effective in vitro against Gram-positive bacteria and Candida albicans , but…
General information 1,2,6-hexanetriol is used as a humectant, solvent, and viscosity-controlling agent in medicaments and cosmetics. Some drug delivery systems involve the use of poly(ortho esters), prepared by the condensation of 1,2,6-hexanetriol and an alkyl orthoacetate [ ]. You’re Reading…
General information Hexachlorophene has been extensively used as an ingredient of innumerable kinds of consumer goods and medical formulations. Since 1961, when it was reported that daily bathing of newborn infants with a 3% hexachlorophene suspension prevented colonization of the…