Meyler's Side Effects of Drugs

Ion exchange polymers

General information Ion exchange polymers are insoluble organic polymers, which trap ions and in doing so release others [ ]. There are four main types: strongly acidic compounds, which typically contain sulfonic acid groups (for example, the polystyrene sulfonates, which…

Iodopropynyl butylcarbamate

General information Initially used as a preservative in wood paints and metal-working fluids, 3-iodo-2-propynyl butylcarbamate is also used in cosmetics, shampoos, metal-working fluids, and moistened wipes [ ]. You’re Reading a Preview Become a Clinical Tree membership for Full access…

Iodine-containing medicaments

See also Amiodarone ; Iodinated contrast media ; Iodopropynyl butylcarbamate ; Radioactive iodine General information Iodine is a non-metallic halogen element (symbol I; atomic no 53, atomic weight 127). It exists as a near-black solid but readily sublimates, giving a…

Iodinated contrast media

See also Amiodarone ; Iodine-containing medicaments ; Iodopropynyl butylcarbamate ; Povidone-iodine; Radioactive iodine General information The radio-opacity of X-ray contrast media depends on the fact that they contain substances with high atomic weights that absorb X-rays. Bismuth, now largely obsolete,…

Interleukin-12

General information Interleukin-12, an immunomodulatory cytokine, has potential effects in several cancer and infectious diseases. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in…

Interleukin-11

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Interleukin-10

General information Interleukin-10 is a potent anti-inflammatory and immunosuppressive cytokine with beneficial effects expected in a wide range of diseases [ ]. In healthy volunteers, its adverse effect profile mostly consisted of flu-like symptoms at the highest dose [ ].…

Interleukin-6

General information Interleukin-6 is produced by T cells, monocytes, fibroblasts, endothelial cells, and keratinocytes, and regulates pleiotropic biological functions. Recombinant interleukin-6 has been evaluated for thrombopoietic and antitumor properties [ ]. General adverse effects and adverse reactions During clinical trials,…

Interleukin-4

General information Interleukin-4 is a pleiotropic cytokine, mostly produced by activated T cells, which acts on the proliferation and differentiation of B and T lymphocytes and enhances the function of natural killer cells, eosinophils, and mast cells [ ]. It…

Interleukin-3

General information Interleukin-3 is produced by activated T lymphocytes and stimulates the proliferation and differentiation of the granulocyte, macrophage, eosinophil, basophil, erythroid, megakaryocyte, and mast cell lineages [ ]. Drug studies Observational studies Subcutaneous recombinant interleukin-3 has been investigated in…