General information Isoflurane is a potent inhalation anesthetic. An isomer of enflurane, it has many of the same adverse effects. It is hardly metabolized (about 0.2%), which has encouraged its prolonged use as a sedative agent or bronchodilator in patients…
General information Isoetarine is a beta-adrenoceptor agonist bronchodilator given orally in a modified-release formulation [ ]. It is slightly more beta 2 -selective than isoprenaline but has a beta-blocking metabolite. When isoetarine was compared with salbutamol in the treatment of…
See also Aminoglycoside antibiotics General information Isepamicin is similar to amikacin but has better activity against strains that produce type I 6′-acetyltransferase. It can cause nephrotoxicity, vestibular toxicity, and ototoxicity. However, it is one of the less toxic of the…
See also Iron oxide General information Iron is a metallic element (symbol Fe; atomic no. 26). The symbol is derived from the Latin word for iron, ferrum. Iron is found widespread in nature in ores such as almandine hercynite (iron…
General information Ultrasmall superparamagnetic particles of iron oxide (USPIOs) of median diameter no less than 50 nm have been studied as blood-pool agents and are given intravenously to enhance liver imaging in patients with cirrhosis and to visualize lymph nodes.…
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See also Angiotensin II receptor antagonists . General information Irbesartan is a potent selective angiotensin II type 1 (AT 1 ) receptor antagonist. Its pharmacology is the same as that of other angiotensin II receptor antagonists [ ]. In the…
See also Tricyclic antidepressants General information Iprindole is a 6,5,8 tricyclic compound, whose first two rings form an indole nucleus [ ]. It is of some theoretical interest, in that it is weak in its action on the amine pump…
See also Anticholinergic drugs General information Ipratropium hydrobromide is a quaternary amine, the semisynthetic isopropyl derivative of atropine, which has low lipid solubility and is poorly absorbed. It has anticholinergic properties and is used to treat asthma. The metered dose…
See also Rubiaceae General information Ipecacuanha is an extract of the root of Psychotria ipecacuanha , also known as Cephaelis ipecacuanha , a member of the Rubiaceae. It contains the emetic alkaloids cephaeline and emetine. It has often been used…