General information Ketobemidone is an opioid receptor agonist, with pharmacokinetics and potency similar to morphine. Combined with the antispasmodic drug, N,N-dimethyl-3,3-diphenyl-1-methylallylamine chloride, ketobemidone is often used in Scandinavia. In a study of postoperative pain relief, ketobemidone equalled morphine and pethidine…
General information Ketanserin is a selective 5-HT 2 receptor antagonist with antihypertensive action. Because it antagonizes the vasoconstriction and platelet aggregation induced by 5-HT and increases erythrocyte deformability, its potential usefulness in peripheral vascular disease has been extensively investigated, although…
General information Ketamine is a non-competitive antagonist at the phencyclidine site of the N-methyl- d -aspartate (NMDA) receptor for glutamate. However, its effects are also mediated by interactions with many others receptors. It is a short-acting anesthetic that has been…
See also Non-steroidal anti-inflammatory drugs (NSAIDs) General information Kebuzone (ketophenylbutazone, ketazone) is an NSAID that is related to phenylbutazone. Allergic reactions, gastrotoxicity, nephrotoxicity, local reactions with necrosis [ ], and liver damage have been reported [ ]. The Japanese authorities…
General information Kaolin is commonly given together with pectin in the treatment of diarrhea, and can be combined with an opioid such as morphine. It has also been used in poultices an in hemostatic dressings [ ]. You’re Reading a…
See also Aminoglycoside antibiotics General information Kanamycin can be used for short-term treatment of severe infections caused by susceptible strains (for example Escherichia coli , Proteus species, Enterobacter aerogenes , Klebsiella pneumoniae , Serratia marcescens , and Mima-Herellea ) that…
General information The family of Juglandaceae contains three genera: 1. Carya (hickory, pecan); 2. Juglans (walnut); 3. Pterocarya (pterocarya). Carya spp You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If…
See also Macrolide antibiotics General information In a randomized open study, 325 children aged 2–15 years with acute tonsillitis and a positive test for Streptococcus pyogenes antigen were treated with josamycin 25 mg/kg bd for 5 days, or penicillin 50…
General information Japanese encephalitis is an important arboviral disease in man in Japan, China, Korea, Thailand, India, Nepal, Sri Lanka, and Vietnam. In 1954, Japanese encephalitis vaccine of the mouse brain type for human use was licensed in Japan. However,…
General information Ivermectin, a dihydroavermectin B1, is an effective microfilaricide used in the treatment of strongyloides, scabies, and all types of filariasis except Dipalonema ( Mansonella ) perstans infections. Over a number of years, ivermectin has shown excellent results in…