See also Leflunomide and teriflunomide General information Synthetic malononitrilamides have been derived from A77 1726, the active metabolite of leflunomide. Of these, manitimus (malononitrilamide 715; FK778) is the most promising, because of its much shorter half-life. Manitimus blocks de novo…
See also Calcium channel blockers General information Manidipine is a dihydropyridine calcium channel blocker that can be given once a day for hypertension. In a comparison of manidipine 10 mg/day and amlodipine 5 mg/day in a multicenter, randomized, double-blind study…
General information Manganese is a hard but brittle grayish-white metallic element (symbol Mn; atomic no. 25) that occurs in nature chiefly in the form of its oxides, but is also found as a sulfide (for example in alabandite), carbonate (ankerite,…
General information The genera in the family of Malvaceae ( Table 1 ) include cotton, okra, and various types of mallow. Table 1 Genera of Malvaceae Abelmoschus (okra) Abutilon (Indian mallow) Alcea (hollyhock) Allosidastrum (mock fanpetals) Allowissadula (false Indian mallow)…
General information Malathion is used for the treatment of lice, a single application of 0.5% in a solution being customary. Used in this way, it is generally safe, although the same compound has caused fatal poisoning when used as a…
General information For many years attempts have been made to find a vaccine against malaria, especially malaria tropica [ ]. Most of these attempts have been disappointing [ , ]. However, the results of a number of field studies have…
See also Laxatives General information Magnesium is a bright, silver-white alkaline earth metallic element (symbol Mg; atomic no. 12). It is widely found as different salts in minerals such as boracite (borate), ankerite and dolomite (carbonates), carnallite (chloride), brucite (hydroxide),…
See also Sulfonamides General information Mafenide is a topical sulfonamide that has been used for the treatment of burns but is now obsolete. Organs and systems You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy…
See also Granulocyte colony-stimulating factor (G-CSF) , Granulocyte–macrophage colony-stimulating factor (GM-CSF) , and Myeloid colony-stimulating factors General information Macrophage colony-stimulating factor (M-CSF) stimulates the growth and differentiation of the monocyte lineage, and promotes the survival, proliferation, and functions of mature…
See also Methadone General information The basic structure of the macrolide antibiotics is characterized by a lactonic cycle with two osidic chains, and they are classified according to the number of carbon atoms in the cycle: 14-membered macrolides (for example…