See also Antihistamines General information Oxatomide is a second-generation antihistamine [ ]. Organs and systems You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in…
General information In controlled studies, oxaprozin caused adverse effects in 23–58% of patients [ ]. It was considered better than aspirin and similar to other NSAIDs in long-term studies [ ]. However, treatment had to be interrupted owing to adverse…
General information Oxamniquine, in doses of 15 mg/kg or in a single oral dose of up to 15 mg/kg bd for 2 days, depending on the sensitivity of Schistosoma mansoni in the area concerned, is effective with minimal toxicity. It…
See also : Non-steroidal anti-inflammatory drugs (NSAIDs) General information The adverse reactions pattern of oxametacin is similar to that of indometacin. In one study, 17% of 771 patients taking oxametacin had adverse effects, which led to withdrawal of treatment in…
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See also Factor Xa inhibitors, direct General information Otamixaban is direct factor Xa inhibitor [ , ]. Its pharmacokinetics have been studied in healthy men over a wide range of intravenous doses, with durations of administration varying between 1-minute infusions…
General information Osmic acid is injected into joints for chemical synovectomy [ ]. It is associated with local pain, effusions, and fever; skin necrosis is less frequent [ ]. Nerve damage and abnormal urinary findings (hematuria, proteinuria, and leukocyturia) can…
See also Adrenoceptor agonists General information Orphenadrine is related to an antihistamine (diphenhydramine), and appears to have been developed in the hope of producing a greater effect in Parkinson’s disease by combining both anticholinergic and antihistaminic effects in a single…
See also Benzimidazoles General information Used in single large doses for the treatment of Trichomonas urogenitalis or Giardia infections, ornidazole can cause gastrointestinal symptoms [ ]. Organs and systems Cardiovascular Cardiac arrest has been attributed to intravenous ornidazole in a…
General information Mannitol is an osmotic diuretic that has been used in acute oliguric renal insufficiency, acute cerebral edema, and the short-term management of glaucoma, especially to reduce intraocular pressure before ophthalmic surgery. Other indications include promotion of the excretion…