See also Neuromuscular blocking drugs, non-depolarizing General information Pancuronium bromide is a non-depolarizing muscle relaxant [ ] with two quaternary ammonium groups on a steroid (androstane) skeleton. It is about 5–7 times as potent as d -tubocurarine. Protein binding occurs…
General information Pancreatic enzyme supplements are used to treat people who lack pancreatic secretions. Pancreatin is an extract of pancreas, and contains enzymes with proteinase, amylase, and lipase activity; most commercial formulations are similar or identical [ ]. Drug studies…
See also Monoclonal antibodies General information Palivizumab is a humanized monoclonal antibody that inhibits an epitope at the A antigenic site of the F protein of respiratory syncytial virus subtypes A and B [ , ]. The most common adverse…
See also Neuroleptic drugs General information Paliperidone, or 9-hydroxyrisperidone, is the major active metabolite of risperidone. It binds to both dopamine D 2 and serotonin 5HT 2A receptors, and antagonism at these receptors is thought to account for its therapeutic…
See also Cytotoxic and immunosuppressant drugs General information Paclitaxel is a complex plant product derived from the bark of the yew tree, Taxus brevifolia . It has been used for the treatment of metastatic carcinoma of the ovary and breast.…
General information Oxytocin is a hypothalamic nonapeptide that selectively stimulates the smooth muscle of the uterus and mammary glands. It is used in the induction or augmentation of labor and to prevent postpartum hemorrhage, and is well tolerated and effective…
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General information Oxymetazoline and xylometazoline are alpha-adrenoceptor agonists used topically as nasal decongestants [ ]. They have higher affinities for most α-adrenoceptor subtypes than adrenaline and noradrenaline. Oxymetazoline has a significantly higher affinity for α 1A receptors than xylometazoline but…